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Vitamins (E, C and beta-carotene)

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By: Sean Moloughney

Editor, Nutraceuticals World

Indication: Prostate cancer

Source: J Natl Can Inst, February 15, 2006;98(4)245-254.

Research: Researchers evaluated the association between intake of these antioxidant vitamins from foods and supplements and the risk of prostate cancer among men in the screening arm of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. At baseline, nearly 30,000 trial participants completed a 137-item food frequency questionnaire, which included detailed questions on 12 individual supplements.

Results: Approximately 1338 men were diagnosed with prostate cancer within eight years of entering the study. Supplement users were just as likely to be diagnosed as nonusers. However, smokers were 71% less likely to be diagnosed with advanced disease if they had taken high doses of vitamin E for many years. Re-searchers said the results do not provide strong support for population-wide implementation of high-dose antioxidant supplementation for the prevention of prostate cancer. However, they said, vitamin E supplementation in male smokers and beta-carotene supplementation in men with low dietary beta-carotene intakes were associated with reduced risk of this disease.

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